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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRK
All Species:
26.67
Human Site:
Y186
Identified Species:
58.67
UniProt:
P46108
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46108
NP_005197.3
304
33831
Y186
R
G
M
I
P
V
P
Y
V
E
K
Y
R
P
A
Chimpanzee
Pan troglodytes
XP_001154201
304
33657
Y186
R
G
M
I
P
V
P
Y
V
E
K
Y
R
P
A
Rhesus Macaque
Macaca mulatta
XP_001086006
296
33190
P179
E
K
L
V
R
S
S
P
H
G
K
H
G
N
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64010
304
33796
Y186
R
G
M
I
P
V
P
Y
V
E
K
Y
R
P
A
Rat
Rattus norvegicus
Q63768
304
33826
Y186
R
G
M
I
P
V
P
Y
V
E
K
Y
R
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521366
302
33449
Y184
R
G
M
I
P
V
P
Y
V
E
K
Y
R
P
A
Chicken
Gallus gallus
Q04929
305
33787
Y187
R
G
M
I
P
V
P
Y
V
E
K
C
R
P
S
Frog
Xenopus laevis
P87378
296
33391
Y179
R
G
M
I
P
V
P
Y
V
E
K
Y
R
P
P
Zebra Danio
Brachydanio rerio
NP_001003628
311
34245
P193
P
Y
V
E
K
Y
R
P
A
S
P
T
S
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XYM0
271
31186
I156
S
S
G
K
I
G
Q
I
P
V
P
Y
I
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9NHC3
279
30860
G164
R
N
A
L
G
T
T
G
L
V
P
A
N
Y
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
62.5
N.A.
N.A.
99.6
99.6
N.A.
82.8
84.9
83.2
69.4
N.A.
46.3
N.A.
31.5
N.A.
Protein Similarity:
100
96
74
N.A.
N.A.
100
100
N.A.
85.8
90.8
89.8
79.7
N.A.
60.5
N.A.
47.7
N.A.
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
100
86.6
93.3
6.6
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
26.6
N.A.
N.A.
100
100
N.A.
100
93.3
93.3
13.3
N.A.
6.6
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
10
0
0
10
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
0
0
0
0
0
64
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
64
10
0
10
10
0
10
0
10
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% H
% Ile:
0
0
0
64
10
0
0
10
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
10
10
0
0
0
0
0
73
0
0
0
0
% K
% Leu:
0
0
10
10
0
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
64
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
10
10
0
% N
% Pro:
10
0
0
0
64
0
64
19
10
0
28
0
0
64
10
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% Q
% Arg:
73
0
0
0
10
0
10
0
0
0
0
0
64
0
10
% R
% Ser:
10
10
0
0
0
10
10
0
0
10
0
0
10
0
10
% S
% Thr:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
0
% T
% Val:
0
0
10
10
0
64
0
0
64
19
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
10
0
64
0
0
0
64
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _